The Breathing Together project has an excellent PhD studentship available:
Visit this link to find an exciting PhD studentship opportunity in the Centre for Experimental Medicine, Queen’s University Belfast: http://www.findaphd.com?pj=84457.
CLOSING DATE – June 11th, 2017.
Project Title: Paediatric airway epithelium in health and disease: Comparative responses of airway epithelium from healthy and wheezing children to viral and allergen insults
This project will be part of a Wellcome Trust Strategic award involving 7 major UK universities and University of Lausanne. It provides an exceptional opportunity for an excellent and highly motivated student to study the consequences of respiratory virus infection and allergen exposure on airway epithelium from infants with or without wheeze/asthma and atopy. Asthma is predominantly a childhood onset disease affecting over 300 million people worldwide, and over a million UK children.
Lung defects in asthmatic children at 6 years may be sustained into adulthood. The first six years of life are therefore critical in determining adult lung function and interactions between structural airway abnormalities, infantile viral infections, and atopy/allergy are key influences. All children undergo multiple infections and allergen exposure in early life. Some will wheeze following infection/allergen exposure and many will not. Of the wheezers, some will outgrow the wheeze, while others will develop asthma that is sustained into adulthood. We cannot predict which outcome will prevail. This project will employ state-of-the-art 3-D primary infant airway epithelium cultures to replicate the pathophysiological consequences of respiratory virus infection and/or allergen exposure in human airways. These studies will provide a comprehensive understanding of the cytopathological events and molecular mechanisms in airway epithelium that are associated with the development of respiratory virus- and/or allergen-induced pre-school wheeze.
Supervisors: Dr. Ultan Power, http://pure.qub.ac.uk/portal/en/persons/ultan-power(889d88df-81fb-485b-99cc-74712b8ea19d).html
Candidates should have or expect to obtain a 2:1 or higher Honours degree or equivalent in a relevant biomedical or life sciences subject.
Candidates applying from countries where the first language is not English should produce evidence of their competence through a qualification such as IELTS or TOEFL score.
Read about the Centre for Experimental Medicine here: http://www.qub.ac.uk/research-centres/CEM/